G-Protein Coupled Receptors


     G-protein-linked receptors form the largest family of cell-surface receptors and are found in all eucaryotes. About 5% of the genes in the nematode C. elegans, for example, encode such receptors, and thousands have already been defined in mammals; in mice, there are about 1000 concerned with the sense of smell alone. G-protein-linked receptors mediate the responses to an enormous diversity of signal molecules, including hormones, neurotransmitters, and local mediators. 


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