Anatomia omului [65]
Anatomia topografica [30]
Anestezie/Reanimare [17]
Alergologie [10]
Biochimia [38]
Biochimie Clinica [8]
Biofizica [14]
Biologie moleculara [28]
Biostatistica [7]
Boli Infectioase [12]
Boli infectioase la copii [27]
Boli profesionale [1]
Cardiologie [54]
Chimie bioorganică [4]
Chirurgie [65]
Chirurgia OMF [4]
Chirurgia pediatrica [15]
Cultura comunicarii [0]
Kinetoterapie [10]
Dermatologie [34]
Ecologie [2]
Endocrinologie [15]
Epidemiologie [9]
Examen de Stat USMF [18]
Farmacologie [30]
Filosofie si bioetica [19]
Fiziologia umana [41]
Fiziopatologie [37]
Ftiziopneumologie [11]
Gastroenterologie [34]
Genetica umana [39]
Geriatrie [2]
Ginecologie [22]
Igiena generala [29]
Imunologie [9]
Hematologie [31]
Hepatologie [5]
Histologie [18]
Medicina interna- Terapie [60]
Medicina de Familie [23]
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Medicina sociala [2]
Microbiologie [14]
Morfopatologie [40]
Nefrologie [28]
Neurologie [25]
Neonatologie [16]
Nursing [7]
Obstetrica [28]
Oftalmologie [11]
ORL [11]
Oncologie [9]
Parazitologie [29]
Pediatrie si Puericultura [156]
Pneumologie [37]
Psihiatrie [56]
Psihologie [24]
Radiologie si Imagistica [38]
Reumatologie [33]
Sexologie [1]
Stomatologie [33]
Traumatologia si ortopedia [24]
Urgențe medicale [32]
Urologie [24]

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Curs: Lupus erythematosus


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Lupus erythematosus 


*Lupus erythematosus (LE) is an autoimmune disease of unknown cause involving the skin and/or other organs.
*LE is the designation of a spectrum of diseases that are linked by distinct clinical findings and distinct pattern of polyclonal B cell immunity.
*It ranges from life-threatening manifestations of systemic LE (SLE) to the limited and exclusive skin involvement in chronic cutaneous LE (CCLE).
*Lupus erythematosus is a complex and highly variable disease in which a combination of genetic, immunologic and environmental factors acts in concert with the production of the disorder. 
*Systemic LE (SLE)
-acute cutaneous LE (ACLE): malar rash, discoid rash, photosensitivity, oral ulcers
-arthritis: nonerosive involving two or more peripheral joints
-serositis: pleuritis; pericarditis
-renal disorder: persistent proteinuria; cellular casts
-neurologic disorder: seizures; psychosis
-hematologic disorder: hemolytic anemia; leukopenia; lymphopenia; thrombocytopenia  
-immunologic disorder: anti-DNA, anti-SM and antiphospholipid antibodies
-antinuclear antibody: abnormal titer of antinuclear antibodies 
*Cutaneous LE (CLE)
-subacute cutaneous LE (SCLE)
-chronic cutaneous LE (CCLE)
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